Category: DNA

Continuing Genealogical Studies: Genetic Genealogy, the Basics – Review

The National Genealogical Society (NGS) has a number of classes for genealogists to take. Their Home Study Course (now called American Genealogical Studies) I took about a year ago and highly recommend. It is a wonderful course for people just starting to get more serious about their genealogy and wishing to take it beyond the internet.

Because of how much I enjoyed that course, I wanted to dive into a few more. The NGS has Continuing Genealogical Studies classes that include researching for Revolutionary War ancestors, Civil War research, and genetic genealogy. They just recently added a course called Genetic Genealogy, Autosomal DNA, which caught my eye, but I decided to take their Genetic Genealogy, the Basics first, since I figured it may help in the autosomal course. Plus, the last time I took a course on genetics was in college in 2001. So, it’s been a while and a refresher sounded like a good idea!

By Jerome Walker,Dennis Myts (Own work) [Public domain], via Wikimedia Commons

By Jerome Walker,Dennis Myts (Own work) [Public domain], via Wikimedia Commons

The Goals and Cost of the Course

The course is for beginner and intermediate level students and is designed to teach:

  • the DNA molecule
  • chromosome basics
  • DNA markers (SNP and STR)
  • Y DNA and surname projects (basic information)
  • mitochondrial DNA and mtDNA testing

The course contains 6 modules, each ending with a short quiz of about 5-10 questions. You have 6 months to complete the course on your own time with a one-time 3 month extension possible if need be. It is all online and done through the NGS Canvas system (it uses this for other online courses as well).

The course has been created by Thomas H. Shawker, MD. He is a physician who has served on the NGS Genetic Genealogy Committee as a chairman, is a prominent speaker, and is the author of the book Unlocking Your Genetic History.

There are two prices for this course as with all NGS courses – one for members and one for non-members. For non-members the cost is $70 and for members it is $45.

Pros

  • The course starts from the basics: the human cell and where DNA lives inside of it, and explains from there
  • The course gives a good foundation on where genetic genealogy looks when it comes to DNA testing for genealogy
  • It explains many of the terms found in genetic genealogy
  • It is chock full of information to get anyone going on a Y DNA surname project or mtDNA testing

Cons

  • Some small items are left out or not explained well. For clarification, I sought out the International Society of Genetic Genealogy Wiki for clarification.
    • For example, I did not realize (forgotten over the years really) that humans share 99.9% the same genome as other humans. There are small mutations (like SNPs which are discussed in the course) which causes each person to look different from another. I was lost because 1) I thought our genome was MUCH different than everyone else’s and was confused on how genetic scientists knew where to look and 2) I couldn’t understand how the human genome could have been mapped if we all looked so different (assuming again that our genomes were vastly different from each other). Knowing that small fact that all humans share 99.9% the same genome made it all make sense to me.
    • Another example: the mtDNA test – for some reason I had thought this was the X chromosome we all get from our mother. But then I was confused because well, which x chromosome are we getting? And how do we know it’s always from the maternal line? I didn’t realize that mtDNA is NOT the X chromosome and had to look at the ISOGG wiki for that clarification. I feel silly stating all of that as I’m sure most people know that, but for those of you who didn’t, I was right there with you!
  • The quizzes. You have 5-10 questions and you can retake them up to 3 times. The problem is that after you take it once, the quiz shows you your score ALONG WITH THE ANSWERS (no matter if you got it right or wrong). So you can just retake it and get everything right as the questions don’t change when you retake the quiz. Maybe it’s the teacher in me, but I felt that made the quizzes irrelevant.
  • This is a short course. You can probably finish the course in a day if you felt so inclined. I did mine over a few days and spent maybe an hour or two on the course each day. For the cost, especially as a non-member, I felt this was a downfall. I expected more.

Overall

Overall, I learned a LOT coming out of this course. I feel much better about my understanding of the two DNA tests that it focused on – Y DNA and mtDNA. I know I still have more to learn but the basics did give me a good foundation to start on and I feel much more knowledgeable about the terms and have found reading about DNA easier to understand now. I do recommend the course, although I wish it was less expensive. And I recommend taking the course ALONG with reading the terms on the ISOGG Wiki. It helps for clarification and gives a better understanding. Not to mention the ISOGG Wiki is a website you’ll want to bookmark to return to in the future.

For the cost, as I said, I did expect more. However, I realize that I may be alone in this. There are hundreds of courses out there all at varying prices. This is probably one of the cheapest  ways of learning more if you prefer the structure of a class, like I do. Of course, I encourage you to seek more information from books and online resources, but this can be a great way to get started in your genetic genealogy education.

Mystery Monday: DNA Connection – But Where?

I shared a while ago about my grandparents getting their DNA tested for me and that I had been impatiently waiting for results. Those results had actually finished quite some time ago and I’ve been slowly learning and playing with the results. I haven’t done enough to merit a blog post… yet.

My chromosome browser with my maternal grandparents selected

My chromosome browser with my maternal grandparents selected – It isn’t surprising that I share more segments with my grandmother; I definitely take after her 🙂

 

I do make sure to always answer emails about possible connections (something I have heard isn’t done as often as others would like). One thing immensely neat about having my grandparents DNA is that I can begin to narrow down connections as well!

To explain, I was emailed by someone, we’ll call him John Doe for the moment, saying that we have a 3rd-5th cousin match, which he is hoping may be able to solve some brick walls for him. So, to see what side he is related to, either my dad’s or my mom’s, I can now check to see if he is related to either of my grandparents – and he is! To my grandfather specifically; and he’s listed as being a 2nd-4th cousin. Nice, right? Which means that John Doe and I are probably 4-5th cousins, so we have a 3x or 4x great-grandparent in common.

I LOVE that I can do that now!

John Doe happens to be looking for a very specific geographic location – Canada. The lineage he is going after happens to be French Canadian. This is also excellent because my grandfather’s paternal line  and my grandfather’s maternal grandfather all came over from central Europe; making it much easier to pinpoint what family we may be connected with.

With that, I have it narrowed down a bit. My 4th great-grandmother came from Montreal. Her name is Ellen (Belgard) LaValley. Her parents are Joseph and Sophia (Levereaux ) Belgard – all French Canadian.

So, I may have found the connection. Now comes the mystery – how are the two families connected?

At the moment, he is making a tree with his information, and I’m doing the same with my information and we are hoping to meet somewhere in the middle. And so far… we haven’t.

Of course, there’s always the possibility that I’m chasing down the wrong lineage. There is my 4th great-grandmother, Martha (Dean) Pape, whom I can’t yet confirm her parents names, and therefore can’t say for sure that her lineage is not French Canadian.

The line could also come from the LaValley’s, whom I only have as far as Joseph, Ellen Belgard’s husband, who came from New York but whose family could also be from Canada.

So many choices! Just think if I couldn’t have narrowed it down as much as I had! A moral of this story – get your family members tested! And as far back as you possibly can!

I did hear that my 2nd great-aunt is still alive (sister to my great-grandmother – and connected to the line I’m currently chasing), but I’ve never met her and I think it may not go well if I showed up and asked her to spit in a tube… 🙂

 

Stay tuned for more on this mystery! It has become my research focus for September!

 

 

Tuesday’s Tip: GEDmatch.com

If you’ve had your DNA tested with one of the three major companies (AncestryDNA, 23andme, or FamilyTreeDNA), you should be using GEDmatch as well! GEDmatch is a FREE website where you can upload your raw DNA data if you tested with one of those three companies and use their tools for genetic genealogy! Plus, adding your DNA to another database is absolutely worthwhile in finding as many connections as possible!

GedMain

Registering is very simple – you give a first and last name (optional alias), email address, and a password. Once you’re set up, you can upload your raw DNA:

Ged1

Clicking on the test you used will bring up the upload page. Each page has either instructions there or a link to detailed instructions on how to get your raw DNA and how to then upload it to the system. It’ll take a bit to have the information processed, which I believe varies. While waiting for it to be processed (or before you upload), I highly recommend going through the Learn More section which includes:

The DNA for ‘Dummies’ section has WONDERFUL information for those who are just getting started in genetic genealogy. It’s a list of of resources that explain how to use GEDmatch, explains Autosomal DNA, discusses the X-Chromosome, and more.

Once your DNA has been processed, there are several fun things you can then do!

  • You can look at your admixture (which has many options – here I highly recommend reading through Kitty Cooper’s slides and explanations on this as well) – here is an example of mine using the MDLP Project, admixture proportions with link to oracle, and the World 22 calculator (it pretty much matches what AncestryDNA and FamilyTreeDNA say):

Ged2

  • You can compare your DNA to others in the database using a one-to-many comparison (you decide the CentiMorgan range to narrow down your results), or a one-to-one match (where if you know someone else’s DNA kit number and you want to compare it to yours).
  • There is also a 3D chromosome browser you can use (see below for a link that explains how to use that)
  • and LOTS more like “Are your parents related?” and “What color are your eyes?”

I am still learning about genetic genealogy and am by no means an expert, FYI. GEDmatch is something I am still learning how to use and how to apply that to genealogy but it’s a great tool for those interested in genetic genealogy!

Here are other resources that discuss using GEDmatch:

 

If I missed anything you want to add put it in the comments or leave a comment on my FB page!

Wordless Wednesday: DNA Has Arrived!

I want to share this with people who will hopefully understand 🙂 I signed in to FamilyTreeDNA to check on my grandparents DNA test to see if it arrived yet and I found this:

Excitement

Did you see that? Right there!

excitement 2

It was received MONDAY!

 

So… anyone know how long it takes for it to be processed?

 

If you need me, I’ll be impatiently waiting by my computer. 🙂

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